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Snap-8

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Summary

Acetyl Octapeptide-3, Snap 8

Snap-8 is a synthetic peptide used in topical skincare products, designed to work on facial muscle contraction. Research has proposed that it modulates nerve signaling involved in muscle movement when applied to skin. It's formulated into various cosmetic products as an ingredient studied for effects on expression lines and facial wrinkles.

Current Research
  • Facial muscle contraction signaling
  • Cosmetic dermatology research
  • Expression-line biology
Identification
CAS
868844-74-0
Formula
C41H70N16O16S
M.W.
1075.2 g/mol

Key Research Statistics

Topical Anti-Wrinkle

0%Systemic AbsorptionTopical only — no injection, no systemic side effects
28 daysVisible ResultsWith consistent daily topical application
Wrinkle Reduction by Concentration (28 Days)
Topical application, manufacturer study
SNAP-8 (10%)63%
SNAP-8 (5%)48%
SNAP-8 (3%)34%
Placebo4%
Lipotec clinical studies
vs Other Anti-Wrinkle Compounds
Wrinkle reduction comparison across methods
Botox (Injection)90%
SNAP-8 (Topical)63%
Retinoids (Topical)35%
Argireline (Topical)30%
Cross-study comparison

Need-to-Know

  • Room Temperature (Lyophilized): 4-8 weeks
  • Refrigerated (Reconstituted): 14-21 days
  • Frozen (Lyophilized): 6-12 months
  • Reconstitution Solution: Sterile water, Distilled water
  • Appearance: White powder

Regulatory Status

Not FDA-approvedInvestigationalPreclinical

Acetyl Octapeptide-3 in research for anti-aging and muscle relaxation applications.

Sources: FDA.gov, CIR

History

2000s
Developed in late 2000s as improved topical wrinkle peptide.
2010s
Studies showed up to 63% wrinkle reduction in 28 days; widely used in skincare.
2020s
Marketed as topical alternative to injections; ongoing research.

3D Structure

8-amino-acid peptide · 1075.2 g/mol

Interactive model
Snap-8 molecule previewExplore 3D Structure

Snap-8 at the Cellular Level

SNARE complex modulator

Mechanism
Snap-8 cellular mechanism preview

Snap-8 in the Body

Acetyl octapeptide-3 (SNARE complex modulator)

Dermal
Snap-8 in the Body

Research Library

Peer-reviewed studies

From Published Literature

"Acetyl Octapeptide-3 is designed to inhibit the SNARE complex formation, potentially attenuating muscle contractions associated with the development of expression lines."

Shin et al.Annals of Dermatology
Verify on PubMed

Complete Your Protocol

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