We’re putting the finishing touches on something special — ordering opens soon. Stay tuned.
← Back to Catalog

Glutathione

Glutathione vial frontGlutathione vial back
Loading...

Summary

GSH, L-Glutathione, Reduced glutathione

Glutathione is the body's most abundant antioxidant, made up of three amino acids. It plays a major role in protecting cells from damage and helping the body eliminate toxins. While oral supplements are popular, research suggests IV or inhaled forms may be more effective for raising glutathione levels in the body.

Current Research
  • Cellular antioxidant defense
  • Detoxification pathways
  • Skin and complexion research
  • Healthy aging models
Identification
CAS
70-18-8
Formula
C10H17N3O6S
M.W.
307.33 g/mol

Key Research Statistics

Master Antioxidant & Detoxification

2xNK Cell ActivityNatural killer cell doubling at 1000 mg/day × 6 months
500+Cellular ReactionsGSH-dependent enzymatic processes — the most abundant intracellular antioxidant
Bioavailability by Administration Route
Why route matters for glutathione
SubQ Injection95%
Liposomal Oral40%
Standard Oral15%
Pharmacokinetic studies
6-Month RCT Outcomes (1000 mg/day)
SubQ administration — gold standard route
NK Cell Activity ↑100%
Blood GSH Increase35%
IL-12 Improved80%
IFN-γ Improved75%
Richie 2015 + HIV immunology study

Need-to-Know

  • Room Temperature (Lyophilized): 1-2 weeks
  • Refrigerated (Reconstituted): 7-14 days
  • Frozen (Lyophilized): 12-18 months
  • Reconstitution Solution: Bacteriostatic water, Sterile water
  • Appearance: White powder

Regulatory Status

Not FDA-approvedInvestigationalResearch

Endogenous antioxidant in research for oxidative stress and cellular health.

Sources: FDA.gov

History

1990s
Recognized as body's master antioxidant; protects cells from damage.
2000s
Studies showed it protects against chemo side effects like nerve damage.
2010s
FDA approved for use in foods.
2020s
Popular as supplement; ongoing health research.

3D Structure

3-amino-acid peptide · 307.33 g/mol

Interactive model
Glutathione molecule previewExplore 3D Structure

Glutathione at the Cellular Level

Master antioxidant

Mechanism
Glutathione cellular mechanism preview

Glutathione in the Body

Tripeptide antioxidant (Glu-Cys-Gly)

Immune
Glutathione in the Body

Research Library

Peer-reviewed studies

From Published Literature

"GSH serves as a crucial detoxification co-substrate and antioxidant, playing a central role in the modification and elimination of potentially hazardous compounds."

Peer-reviewed researchersIndian Journal of Biochemistry & Biophysics
Verify on PubMed

Complete Your Protocol

Complementary compounds from other research areas